Prostate Cancer In Patients Presenting With Lower Urinary Tract Symptoms

Mumtaz Ali, Saeed Ahmed Khan, Naimatullah Tareen

Abstract

Objective •

To determine the frequency of prostate cancer in patients presenting with lower urinary tract symptoms.

Study design

Cross sectional study.

Place & Duration of study

Department of Urology, Jinnah Postgraduate Medical Center (JPMC) Karachi, from January 2018 to December 2018.

Methodology

Patients with age from 50-80 years, having lower urinary tract symptoms (LUTS) for three months or more, IPSS 15 to 35 and serum prostate specific antigen (PSA) > 4 ng/ml were included. Patients with any urological malignancy, previous prostate surgery, prostatitis, urolithiasis, renal failure or active UTI, were excluded. Data was collected on a pre designed form and analyzed using SPSS software.

Results

A total of 125 patients were included. The mean age, International Prostate Symptom Score (IPSS) and PSA were 65.18±8.71 year, 25.59±6.68 and 9.11±7.74 ng/ml respectively. Dysuria was the commonest (n=80 - 64%) LUT symptom. Twenty-eight (22.4%) patients with LUTS were diagnosed as carcinoma prostate. Prostate cancer was barely significantly different in different age groups of the patients. Rate of prostate cancer was high with IPSS above 30.

Conclusions

Nearly 1/4th patients with LUTS had prostate cancer. A high index of suspicion must be exercised in patients if LUTS persist for weeks with high IPSS.

Key words

Prostate Cancer, Lower urinary tract symptoms, Prostate specific antigen.