Cooled Lignocaine Gel For Relieving Pain During Rigid Cystoscopy

Naimatullah Tareen, Muhammad Mansoor, Mumtaz Ali, Arif Ali, Saeed Ahmed Khan

  • Muhammad Mansoor Department of Urology & Transplantation Jinnah Postgraduate Medical Center Karachi



To compare the difference of mean pain score between cooled and room temperature 2% lignocaine applied topically during rigid cystoscopy in male patients.

Study design

Comparative study.

Place & Duration of study

Department of Urology & Transplantation, Jinnah Postgraduate Medical Center (JPMC) Karachi, from January 2018 to December 2018.


Male patients with age between 18 year to 60 year with indication of cystoscopy like hematuria, lower urinary tract symptoms, incontinence, surveillance cystoscopy and DJ stent removal were included in the study. Exclusion criteria were patients allergic to topical lignocaine, active urinary tract infection, urethral stricture, spinal cord injury, narrow urethral meatus and prostatitis. Patients were divided into two groups. In group A cooled 2% lignocaine gel and in group B 2% lignocaine gel at room temperature was instilled into the urethra before cystoscopy. Groups were allotted by envelope lottery method. Data was collected on predesigned form and statistical analysis was performed.


Total of 118 patients were included in the study and divided into Group A and Group B with 59 patients in each group. In group A, the mean age of the patients was 34.44 ±9.52 year (19-55 years) while in group B it was 34.00 ±8.98 year (20-55 years). Mean pain score was 3.95 ±1.41 in group A, while in group B it was 6.31 ±1.82. Application of Student t test showed that there was highly significant difference among the mean pain scores between two groups (P <0.001).


Cooling of 2 % lignocaine at 40C significantly decreased the mean pain score, its severity and discomfort and thus recommended for diagnostic and day care rigid cystoscopy procedures under local anesthesia.

Key words

Rigid cystoscopy, Cooled lignocaine, Pain, Visual Analog Scale (VAS).