Predictive Value of Diabetes in Pregnancy Study Group of India Test For Gestational Diabetes Mellitus

Saima Ismail, Shakira Perveen, Shazia Jabbar, Aneela Habib Sheikh

Abstract

Objective 

To find out the predictive value and accuracy of Diabetes in pregnancy study group of India (DIPSI) test for screening and diagnosis of gestational diabetes mellitus (GDM) taking WHO oral glucose tolerance test (OGTT) 99 criteria as gold standard.

Study design 

Cross sectional study.

Place & Duration of study

Department of Obstetrics & Gynaecology, Dr. Ruth KM Pfau Civil Hospital Karachi, from December 2017 to June 2018.

Methodology

A total of 351 pregnant women between 24 - 32 weeks of gestation were enrolled for the study. All study participants underwent screening for diabetes mellitus by DIPSI test and WHO OGTT 99 criteria. All received 75-gram glucose load orally irrespective of last meal status and again after three days of unrestricted diet, in fasting state. Glucose level was measured after 2-hour and a value of > 140mg/dL was considered as diagnostic of GDM by both the tests.

Results

Mean age of women was 29.38±6.8 year, mean gestational age 28.73±3.05 weeks, and mean body mass index (BMI) 25.97±2.80 kg/m2. Frequency of GDM was 12.8% and 11.68% by DIPSI and WHO 99 criteria tests respectively. Validity of test showed a sensitivity of 82.9%, specificity 96.5%, positive predictive value (PPV) of 75.6%, and negative predictive value (NPV) of 97.7% with accuracy of 94.8%.

Conclusion

GDM is commonly reported during pregnancy which can easily be diagnosed with DIPSI test. This is simple, easy to perform, patient friendly test that is reliable and cost effective.

Key words

Gestational diabetes mellitus, Glucose tolerance test, DIPSI test.