Thyroid Malignancy: 5 years’ Experience

Saad Abdul Razzak, Muhammad Naseem Baloch, Zahid Mehmood, Syed Shafqatullah, Hammar Shahid, Fizzah Khalid

Abstract

Objective

To find out the frequency of various types thyroid carcinomas and their management in a tertiary care hospital of Karachi.

Study design

Descriptive case series.

Place & Duration of study

Department of General Surgery, Jinnah Postgraduate Medical Centre, Karachi, from June 2014 to May 2019.

Methodology

All patients with well differentiated thyroid carcinoma and medullary thyroid carcinoma were included in the study. Patients with anaplastic carcinoma were excluded. Written and informed consent were taken from the patients and data was recorded on a pre-designed form.

Results

Two hundred and thirty-eight patients were included in this study. One-fifty-eight patients were female and eighty male with female to male ratio of 2:1. Papillary carcinoma was found to be the most frequent thyroid carcinoma encountered (n=188 - 79.41%) followed by follicular and medullary carcinoma, 26 (10.50%) and 24 (10.08%) respectively. Various surgical procedures were done to deal with these malignancies, that included completion thyroidectomy (n=138 - 57.9%), completion thyroidectomy with modified radical neck dissection (n=10 - 4.20%), total thyroidectomy (n=31 - 13.02%), total thyroidectomy plus modified radical neck dissection (n=47 - 19.74%) and modified radical neck dissection (MRND) alone in 12 (5.04%) patients.

Conclusions

Papillary carcinoma was the most common thyroid malignancy encountered. Frequency of medullary carcinoma was found almost equal to the follicular carcinoma.

Key words

Thyroid carcinoma, Papillary thyroid carcinoma, Follicular thyroid carcinoma, Thyroidectomy, Modified radical neck dissection.