Frequency and Trends of Colorectal Cancers Among Different Age Groups

Hafiza Noor ul Ain, Bilal Burki, Dileep kumar, Aliya Zehra , Sadia Arshad, Khansa Zehra

Abstract

Objective

To assess the trends of colorectal cancers across various age groups.

Study design

A cross-sectional observational study.

Place & Duration of study

Department of General surgery, Jinnah Postgraduate Medical Centre (JPMC) Karachi, from June 2024 to March 2025.

Methods

The study included patients diagnosed with colorectal carcinoma by biopsy. The data included the demographics of the patients, family history, presenting symptoms, details of histopathology report and grade of the tumor. Comparison of the carcinoma and grade of the tumor among different age groups was made using the Chi-square test. A p-value <0.05 was considered as significant.

Results

The study included a total of 300 patients consisting of 191 males (63.7%) and 109 females (36.3%). There were 59 (19.7%) patients in the age group of 15-30 years, 136 (45.3%) between 31-45 years, 85 (28.3%) from 46-60 years, and 20 (6.7%) above 60-years of age. Grade 2, 3, and 4 tumors were more common among patients of age less than 45-years of age (p=<0.0001).

Conclusion

The frequency of colorectal cancers (CRC) was high in patients between 31 - 45-years of age. The tumors were more common among male patients. Moreover, the young patients present with advanced stage of the tumor, mostly in grade 2 and 3.

Key words

Colorectal cancer, Grade of tumor, Rectal carcinoma.