Serum Ca-125 Level In Patients With Endometriosis

Sumera Meer, Gulfishan Haq, Saima Sheikh

  • Gulfishan Haq Department of Obstetrics & Gynaecology Dow Medical College & Civil Hospital Karachi



To determine the frequency of increased serum cancer antigen 125 (CA-125) in patients with endometriosis.

Study design

Cross sectional study.

Place & Duration of study

Department of Obstetrics & Gynaecology, Civil Hospital Karachi, from January 2019 to July 2019.


A total of 85 women with endometriosis, 18 years to 40 years of age were included. Patients with pelvic inflammatory disease, liver disease, those treated for gynecological malignancy and pregnant women were excluded. The blood samples were obtained for serum CA-125 levels. 


The mean age of the patients was 27.01±4.94 year. Majority (n=65 - 76.47%) of the patients were between 18 years to 30 years of age. Mean height was 154.33±12.33 cm, mean weight 76.43±6.61 kg, mean BMI 28.29 ± 3.14 kg/m2 and mean CA-125 level was 77.76±8.91 mIU/ml. Frequency of increased serum CA-125 was found in 60 (70.59%) patients with endometriosis.


Level of serum CA-125 was found significantly high in patients with endometriosis.

Key words

Endometriosis, Serum CA-125, Tumor markers.